AGR2 and CYB5R2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

AGR2

CYB5R2

Description anterior gradient 2, protein disulphide isomerase family member cytochrome b5 reductase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Residual cognition ( 28441426)
  • Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes 87 interacting genes: ANKRD11 APOBEC3B APP ASPH BORCS8 BORCS8-MEF2B BRD7 C3 CAMLG CATSPER1 CCDC90B CD34 CD68 CDKN2AIPNL CETN3 CKAP2 CLIC3 CNNM3 CPNE6 CRCP CREB1 CRMP1 CRYGA CYB5R2 DAG1 DCAF11 EIF3F FABP2 FAM110A FAM117B GET3 GPSM2 GRB2 GUCA1A HCK HMG20A HSD3B7 IL36RN IMPDH2 KLHL38 KRT31 LSM1 LYPD3 MBD3 MBLAC1 MED31 MLH1 NDUFB2 NRF1 NRIP1 NSD1 NTAQ1 NUP54 NUP58 NUP62CL OSTF1 PHC3 POGZ POLR2L POM121 PSMA1 PSMB1 PSORS1C2 PTTG2 RBFOX1 RBP5 RIIAD1 RTL4 RUVBL2 SDC3 SGTA SGTB SH2D1B STK16 TCEA2 TFAP2D THOC1 TLE5 TMEM123 TRAF2 TSTD2 UBE2I UBQLN1 UBQLN2 UBQLN4 USP20 VEZF1 20 interacting genes: AGR2 CDC23 COIL FANCL FFAR2 GOLGA2 HGS MED20 MEOX2 NFKBID PSMC6 REL SUOX TRAF1 TRAF2 TRIM55 TRIM63 TRIP13 YPEL3 ZNF778
Entrez ID 10551 51700
HPRD ID 05896 06435
Ensembl ID ENSG00000106541 ENSG00000166394
Uniprot IDs O95994 Q4JM46 A8K237 Q6BCY4
PDB IDs 2LNS 2LNT
Enriched GO Terms of Interacting Partners?
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