ARL6IP5 and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		ARL6IP5	MYCBP2
Description		ADP ribosylation factor like GTPase 6 interacting protein 5	MYC binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of L-glutamate Import Across Plasma Membrane Glutathione Metabolic Process Learning Or Memory Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Negative Regulation Of Mitochondrial Membrane Potential Protein Transport L-glutamate Transmembrane Transport Positive Regulation Of Stress-activated MAPK Cascade Neuron Death In Response To Oxidative Stress Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transport Cellular Response To Organic Cyclic Compound Protein Localization To Plasma Membrane L-glutamate Import Across Plasma Membrane	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance
Pathways		Glutamate Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		10 interacting genes: ARL6 CCR2 CCR5 CLN8 KRAS MYCBP2 NOTCH1 PRAF2 SLC1A1 VKORC1	52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		10550	23077
HPRD ID		09303	10104
Ensembl ID		ENSG00000144746	ENSG00000005810
Uniprot IDs		A0A024R371 O75915	O75592
PDB IDs			5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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