HYOU1 and CADM1

		HYOU1	CADM1
Description		hypoxia up-regulated 1	cell adhesion molecule 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Endoplasmic Reticulum Chaperone Complex Extracellular Exosome Endocytic Vesicle Lumen	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Synapse
	Molecular Function	Protein Binding ATP Binding Unfolded Protein Binding Chaperone Binding	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity
	Biological Process	Response To Ischemia Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Positive Regulation Of Cytokine Production T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatogenesis Cell Recognition Cell Differentiation Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Activated T Cell Proliferation Detection Of Stimulus
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors XBP1(S) activates chaperone genes	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Post-bronchodilator lung function in asthma (FVC) ( 32989782)	Adult body size ( 32376654) Anorexia nervosa ( 31308545) Body mass index ( 28552196 31978080 28892062 25673413) Body size at age 10 ( 32376654) Cardiovascular risk factors (age interaction) ( 20838585) Childhood body mass index ( 33045005) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798 32041948) Diastolic blood pressure ( 34074324) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 30598549 28869591) Left-handedness ( 32989287) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 34074324) Thyroid stimulating hormone levels ( 30367059 32769997) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)
Interacting Genes		14 interacting genes: CADM1 CDC42 DPYSL3 IL1R1 IL1RL1 INPPL1 LINC01554 NXPE4 PPP2R1B RBM7 SEL1L TAGLN TMEM245 TP53BP2	8 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 HYOU1 MPP3 PSMA6 SDCBP
Entrez ID		10525	23705
HPRD ID		03448	05746
Ensembl ID		ENSG00000149428	ENSG00000182985
Uniprot IDs		A0A384P5T6 A0A494C039 B3KXH0 B7Z602 B7Z766 Q6IN67 Q9Y4L1	A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5
PDB IDs			3BIN 4H5S
Enriched GO Terms of Interacting Partners?
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