ZBTB18 and POMGNT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ZBTB18	POMGNT1
Description		zinc finger and BTB domain containing 18	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Image		No pdb structure
GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Nuclear Speck	Golgi Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Acetylglucosaminyltransferase Activity Manganese Ion Binding Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Protein O-linked Glycosylation O-glycan Processing
Pathways			Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 O-linked glycosylation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) General risk tolerance (MTAG) ( 30643258) Mercury levels ( 26025379)	Body mass index ( 26426971)
Interacting Genes		10 interacting genes: CTBP1 DNMT3A DNMT3B FCGR2B MYLIP PAK1 PIK3R3 POMGNT1 TSN ZBTB2	12 interacting genes: BRCA1 CD74 CISD2 CXCL8 CXorf66 ERGIC3 LNX1 MBD1 RXYLT1 SOX6 TMEM237 ZBTB18
Entrez ID		10472	55624
HPRD ID		12231	09493
Ensembl ID		ENSG00000179456	ENSG00000085998
Uniprot IDs		Q99592	B7Z7F2 B7Z7Q4 Q8WZA1
PDB IDs			5GGF 5GGG 5GGI 5GGJ 5GGK 5GGL 5GGN 5GGO 5GGP 5XFC
Enriched GO Terms of Interacting Partners?
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