TMEM147 and ENPP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM147	ENPP4
Description		transmembrane protein 147	ectonucleotide pyrophosphatase/phosphodiesterase 4
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein-containing Complex	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Ribosome Binding	Protein Binding Metal Ion Binding Bis(5'-adenosyl)-triphosphatase Activity
	Biological Process		Blood Coagulation Positive Regulation Of Blood Coagulation Purine Ribonucleoside Catabolic Process
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma trimethylamine N-oxide levels ( 28439531) Platelet distribution width ( 32888494)
Interacting Genes		55 interacting genes: ABHD16A ABI3 CD200 CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 DPM3 EBP EFNA4 ENPP4 F11R FFAR2 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PACC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC22A1 SLC22A2 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12	2 interacting genes: TMBIM6 TMEM147
Entrez ID		10430	22875
HPRD ID		17633	16862
Ensembl ID		ENSG00000105677	ENSG00000001561
Uniprot IDs		Q9BVK8	Q9Y6X5
PDB IDs		6W6L	4LQY 4LR2
Enriched GO Terms of Interacting Partners?
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