CDIPT and GJB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDIPT	GJB1
Description		CDP-diacylglycerol--inositol 3-phosphatidyltransferase	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding	Gap Junction Channel Activity Protein Binding Identical Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process CDP-diacylglycerol Metabolic Process	Cell-cell Signaling Nervous System Development Purine Ribonucleotide Transport Gap Junction Assembly Transmembrane Transport Epididymis Development
Pathways		Synthesis of PI	Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs		scyllo-inositol
Diseases
GWAS		Mean platelet volume ( 27863252)
Interacting Genes		57 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BCKDK BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SDCBP SIGLEC12 SLC10A6 SLC16A7 SLC7A1 TLCD4 TMX2 UNC93A VMA21	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		10423	2705
HPRD ID		12063	02367
Ensembl ID		ENSG00000103502	ENSG00000169562
Uniprot IDs		A8K3L7 B3KY94 O14735	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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