BASP1 and GAD2

Number of citations of the paper that reports this interaction (PubMedID 23376695)
2

Data Source:
BioGRID (pull down, pull down)

		BASP1	GAD2
Description		brain abundant membrane attached signal protein 1	glutamate decarboxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Cytoskeleton Plasma Membrane Nuclear Matrix PML Body Nuclear Speck Cell Junction Growth Cone Vesicle Extracellular Exosome	Golgi Membrane Cytosol Plasma Membrane Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding
	Biological Process	Thorax And Anterior Abdomen Determination Gonad Development Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Metanephric Mesenchyme Development Glomerular Visceral Epithelial Cell Differentiation Positive Regulation Of Metanephric Ureteric Bud Development	Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Response To Xenobiotic Stimulus Neurotransmitter Biosynthetic Process
Pathways		RHOF GTPase cycle	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Melanoma ( 28212542) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)	Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Lean body mass ( 28552196)
Interacting Genes		5 interacting genes: AGTR1 ATXN1 GAD1 GAD2 SERPINB5	48 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BASP1 BSND CACNG1 CALM1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A GAD1 HIGD1C LDAF1 LIME1 MAL2 MAP3K8 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TNFRSF10D TSPAN33
Entrez ID		10409	2572
HPRD ID		08389	11817
Ensembl ID		ENSG00000176788	ENSG00000136750
Uniprot IDs		P80723	Q05329 Q5VZ30
PDB IDs			1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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