HMG20A and PTH2R

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		HMG20A	PTH2R
Description		high mobility group 20A	parathyroid hormone 2 receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Parathyroid Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways			Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Parathyroid hormone
Diseases
GWAS		Fasting glucose ( 33402679 34059833) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anthropometric traits ( 30576415) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Metabolite levels ( 23823483) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744)
Interacting Genes		60 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	6 interacting genes: CALM1 DYNLT1 GRHPR HMG20A PTH PTH2
Entrez ID		10363	5746
HPRD ID		16116	03276
Ensembl ID		ENSG00000140382	ENSG00000144407
Uniprot IDs		B4DMG1 Q9NP66	B4DFN8 P49190
PDB IDs
Enriched GO Terms of Interacting Partners?
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