RTN3 and NDRG4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		RTN3	NDRG4
Description		reticulon 3	NDRG family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Apoptotic Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways		Synaptic adhesion-like molecules
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Liver enzyme levels (alanine transaminase) ( 33972514) Oily fish consumption ( 32066663) Pork consumption ( 32066663) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)
Interacting Genes		32 interacting genes: AGTR1 AKAP8 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SHANK3 SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391	41 interacting genes: ADCY9 AGTRAP ALDH6A1 APLNR ARFIP2 ARL6IP1 ATP5PF CACFD1 CDR1 CIDEB CMTM3 CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 DHX38 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 NOL3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A
Entrez ID		10313	65009
HPRD ID		18516	14817
Ensembl ID		ENSG00000133318	ENSG00000103034
Uniprot IDs		A0A024R5C4 O95197	A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs		7BRU
Enriched GO Terms of Interacting Partners?
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