BET1 and GRM3

BET1

GRM3

Description Bet1 golgi vesicular membrane trafficking protein glutamate metabotropic receptor 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging ( 22773346)
  • Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
  • BRCA1/2-negative high-risk breast cancer ( 30323354)
  • Obesity-related traits ( 23251661)
  • World class endurance athleticism ( 26824906)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 27611488)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Brachial circumference ( 22479309)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Feeling worry ( 29500382)
  • Hand grip strength (Mahalanobis distance) ( 32235003)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Neurociticism ( 29500382)
  • Neuroticism ( 29255261)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Seborrheic dermatitis ( 29203360)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 54 interacting genes: ADORA2A ANKS6 AQP6 ASGR2 ASZ1 BCL2L13 CD74 CD79A CGRRF1 CISD2 CLDN7 CLEC10A CRB3 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FAM9B GOSR2 GPR152 GPX8 GRM3 JAGN1 KASH5 KCNJ6 LYPD5 MAGEA6 MFF MGST3 NAPB PLEKHA5 PTGES REEP4 RETREG3 SLC26A6 SLC7A14 SNTG2 SSMEM1 STX1A STX1B STX2 STX4 STX5 TMCO5A TMEM237 TMEM35A TMEM52B TMEM80 TMX2 USHBP1 15 interacting genes: APOA5 BET1 CA3 CALM1 CDK2AP1 CYP51A1 GRIP1 OCM2 PICK1 PPM1A SDCBP SLC22A1 TAMALIN ZNF219 ZNF804B
Entrez ID 10282 2913
HPRD ID 16107 03070
Ensembl ID ENSG00000105829 ENSG00000198822
Uniprot IDs O15155 Q53XK0 A4D1D0 Q14832
PDB IDs 3EGX 1S8M 3SM9 4XAR 5CNK 5CNM 6B7H
Enriched GO Terms of Interacting Partners?
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