STAG1 and MSL2

		STAG1	MSL2
Description		stromal antigen 1	MSL complex subunit 2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Nuclear Body Mitotic Spindle Pole	Nucleoplasm MSL Complex
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Sister Chromatid Cohesion Cell Division Mitotic Spindle Assembly	Protein Ubiquitination Histone H4-K16 Acetylation
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	HATs acetylate histones
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein B levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28892062 25673413) Body shape index ( 34021172) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Central corneal thickness ( 32528159 31798171 29760442) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778 30104761) Dentures ( 31235808) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 30275531) Height ( 25282103) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Multisite chronic pain ( 33830993 31194737) Myocardial infarction ( 33532862) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Plateletcrit ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260) Waist circumference adjusted for body mass index ( 34021172)	Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Apolipoprotein A1 levels ( 32203549 33730874) Autism spectrum disorder or schizophrenia ( 28540026) Blood urea nitrogen levels ( 31152163) C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778 33020668) Estimated glomerular filtration rate ( 31152163) Fibrinogen ( 23969696) HDL cholesterol levels ( 32203549) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31217584) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Schizophrenia ( 28991256 25056061 29483656) Serum alkaline phosphatase levels ( 33547301 33339817) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		13 interacting genes: ASPH CALM1 CEP63 CLDN18 GUK1 MSL2 RAD21 SMAD2 SMAD9 SMC1B STAG2 VDR WFDC5	14 interacting genes: APOBEC3B H2AC18 H2AC20 H2BC21 H3C14 H4C1 PAF1 STAG1 TP53 TRIM8 UBE2D3 YWHAE YWHAG YWHAZ
Entrez ID		10274	55167
HPRD ID		05076	08550
Ensembl ID		ENSG00000118007	ENSG00000174579
Uniprot IDs		Q4LE48 Q8WVM7	Q9HCI7
PDB IDs		5QSM 5QSN 5QSO 5QSP 5QSQ 5QSR 5QSS 5QST 5QSU 5QSV 5QSW 5QSX 5QSY 5QSZ 6QB5 6R7O 6RRC 6RRK 6WG3	4B7Y 4B86
Enriched GO Terms of Interacting Partners?
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