SPRY3 and CREB5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

SPRY3

CREB5

Description sprouty RTK signaling antagonist 3 cAMP responsive element binding protein 5
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Idiopathic osteonecrosis of the femoral head ( 28000841)
  • Iron status biomarkers (transferrin saturation) ( 28334935)
  • Adolescent idiopathic scoliosis ( 31417091)
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (memory) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728)
  • Anxiety in major depressive disorder ( 24047446)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
  • Atrial fibrillation ( 30061737 29892015)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Blond vs. brown/black hair color ( 30531825)
  • Breast cancer ( 29059683)
  • Cataracts ( 34127677)
  • Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
  • Crohn's disease ( 23128233)
  • Diabetic retinopathy ( 21441570)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Ferritin levels ( 33491795)
  • Granulocyte count ( 27863252)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Hand grip strength ( 29691431)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 29403010 32888494 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Pulse pressure ( 27841878 30578418)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Smoking behaviour (cigarettes smoked per day) ( 31217584)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • TPE interval (resting) ( 32386560)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White blood cell count ( 29403010 32888494 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 27 interacting genes: AQP1 BEX2 CATSPER1 CHRD CREB5 GNE GPSM3 HOXA1 HR KPRP KRT34 LCE1A LCE1B LCE1F LCE2B LCE3A LCE3D LCE3E MAPKBP1 MEOX2 NEK6 R3HDM2 SLC39A7 VSNL1 ZDHHC17 ZNF587 ZNF655 132 interacting genes: ADAMTSL4 AJUBA AKAP8L ALPP ANAPC11 ATF2 BATF3 CDPF1 CERCAM CIB4 CNFN COL8A1 CYP21A2 CYSRT1 EFEMP2 FBLN1 FHL3 FOS FOSB FOSL1 FOSL2 FRS3 FST HOXA1 HSD3B7 ID3 IGFBP6 INTS11 JDP2 JUN KIFC3 KPRP KRT15 KRT31 KRT40 KRT83 KRT85 KRT86 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP19-3 KRTAP19-5 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1C LCE2A LCE2C LCE4A LCE5A LGALS13 LITAF LMX1B MDFI MGAT5B MLLT6 MMADHC MTUS2 NADSYN1 NBPF19 NOTCH2NLA PCSK5 PLA2G10 PRDM14 PRR22 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS20 RIMBP3 RNF144B RNF208 SIVA1 SNAPC5 SPATA12 SPOP SPOPL SPRED1 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D TP53BP1 TRAF2 TRIM23 TRIM27 TRIM42 TRIP6 TSGA10 TSPAN4 TSR2 UFSP1 UNKL WWOX ZMAT5 ZNF330
Entrez ID 10251 9586
HPRD ID 03917 09896
Ensembl ID ENSG00000168939 ENSG00000146592
Uniprot IDs O43610 Q6ZUP3 Q02930
PDB IDs
Enriched GO Terms of Interacting Partners?
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