PLIN3 and M6PR

Number of citations of the paper that reports this interaction (PubMedID 9590177)
110

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, two hybrid)

		PLIN3	M6PR
Description		perilipin 3	mannose-6-phosphate receptor, cation dependent
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle	Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Membrane Transport Vesicle Clathrin-coated Endocytic Vesicle Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Cadherin Binding	Transmembrane Signaling Receptor Activity Protein Binding Protein Domain Specific Binding Retromer Complex Binding
	Biological Process	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage	Protein Targeting To Lysosome Receptor-mediated Endocytosis Lysosomal Transport Endosome To Lysosome Transport Secretion Of Lysosomal Enzymes
Pathways		Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle	Lysosome Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Idursulfase Galsulfase	Alglucosidase alfa 1-3 Sugar Ring of Pentamannosyl 6-Phosphate alpha-D-mannose 6-phosphate
Diseases
GWAS		Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)	SjÃ¶gren's syndrome ( 28076899) Total cholesterol levels ( 30275531) Type 1 diabetes ( 34127860)
Interacting Genes		33 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C TUBB4A	13 interacting genes: DUSP12 GGA1 GGA2 GGA3 GIMAP5 HSPA12A JUN KTN1 NINJ2 PLIN3 REN SMCO4 TMPRSS15
Entrez ID		10226	4074
HPRD ID		04080	01106
Ensembl ID		ENSG00000105355	ENSG00000003056
Uniprot IDs		A0A140VJN8 O60664	F5GX30 P20645
PDB IDs			1JUQ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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