MPHOSPH6 and RPS20

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		MPHOSPH6	RPS20
Description		M-phase phosphoprotein 6	ribosomal protein S20
Image
GO Annotations	Cellular Component	Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytosol	Nucleoplasm Cytosol Small Ribosomal Subunit Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Synapse Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding MDM2/MDM4 Family Protein Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Maturation Of 5.8S RRNA	Cytoplasmic Translation Translation Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Nevus count or cutaneous melanoma ( 32341527) Obesity-related traits ( 23251661) Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465) Seasonality and depression ( 30217971)	Height ( 18391951) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469)
Interacting Genes		30 interacting genes: AATF APLP1 ARHGAP18 DNM2 DYNLRB1 EIF3G ERG28 EXOSC10 EXOSC3 EXOSC5 EXOSC7 EXOSC8 FTL GDF9 HSBP1 HSPB1 KNSTRN LRIF1 MTREX NUPR1 PARN RBM48 RPS20 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	22 interacting genes: APP BARD1 CREBBP DUX4 ECT2 HMGB1 IL7R MPHOSPH6 NDRG1 NRAS PALS2 PAXIP1 PIK3CA PLEKHO1 PTEN RABAC1 REEP6 SP3 SUN2 TRAF6 TUBE1 UNG
Entrez ID		10200	6224
HPRD ID		16111	04728
Ensembl ID		ENSG00000135698	ENSG00000008988
Uniprot IDs		H3BNT4 Q99547	P60866
PDB IDs		6D6Q 6D6R 6H25	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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