SORBS3 and IQUB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SORBS3	IQUB
Description		sorbin and SH3 domain containing 3	IQ motif and ubiquitin domain containing
Image
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Acrosomal Vesicle Motile Cilium
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Vinculin Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Smoothened Signaling Pathway Cilium Assembly
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		137 interacting genes: ABI2 ABL1 ADAM15 ADAMTSL4 ADAT3 AKIRIN2 AKT2 ANKS1A ARNT2 C1orf109 CATSPER1 CBFA2T2 CBLB CCDC102B CCDC120 CCDC187 CCDC57 CCDC6 CCHCR1 CCNH CCNL1 CDC23 CDKN2C CFAP206 CHERP COG4 CPEB2 CPNE1 CPNE2 CPNE8 CPSF7 CRACR2A DDX17 DDX6 DIP2A DLG5 DMRTB1 DVL2 DVL3 EFHC1 EFS EIF3H ENKD1 FAM214B FAM53C FASLG FBXL19 FLOT1 FNDC11 FXR1 GAS8 GEM GLRA1 GPANK1 GPKOW GYS1 HGS HNRNPF HNRNPK HNRNPUL1 IMP3 INPPL1 INSC IQUB KANK2 KIAA0408 KIAA1217 KIFC3 MAPK1 MAPK3 MKRN3 MYO15B NAB2 NAF1 NCK1 NCKIPSD NEK6 NFKBID NHSL2 NOTCH3 NRBP1 OIP5 OSGIN1 PAK2 PAK5 PHETA1 PHF1 PIBF1 PLEKHN1 PLOD3 PNMA5 POLE2 POLR1C PPFIA3 PPIL6 PPP1R18 PPP3CC QARS1 RAD51D RBMX RIN1 ROPN1 RUNX1T1 SAFB2 SAXO1 SCNM1 SETD5 SH2D4A SHANK3 SOCS7 SPG21 SRCIN1 SYNPO2L TBC1D22B TCEANC TEAD4 TEPSIN TNS2 TRIM23 TRIM27 TRIM41 TSC1 TSGA10 TSGA10IP TXLNA USP2 VARS2 VCL VPS37B VPS37C WIPF2 ZBED1 ZBTB25 ZBTB7B ZC2HC1C ZC4H2 ZNF414	57 interacting genes: ALX4 ANAPC11 ANKRD23 BHLHB9 BLZF1 CALCOCO2 CEP70 CEP76 CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1
Entrez ID		10174	154865
HPRD ID		11535	08194
Ensembl ID		ENSG00000120896	ENSG00000164675
Uniprot IDs		O60504	A0A024R771 Q8NA54
PDB IDs		2CT3 2DLM 2NWM 2YUP	2DAF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?