G3BP1 and HMGXB3

		G3BP1	HMGXB3
Description		G3BP stress granule assembly factor 1	HMG-box containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Focal Adhesion Cytoplasmic Stress Granule Perikaryon Ribonucleoprotein Complex	Cellular_component Nucleus
	Molecular Function	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity MRNA Binding Endonuclease Activity Protein Binding ATP Binding ATP Hydrolysis Activity DNA/RNA Helicase Activity	DNA Binding
	Biological Process	Ras Protein Signal Transduction Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Stress Granule Assembly Innate Immune Response Defense Response To Virus Positive Regulation Of Stress Granule Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis	Biological_process
Pathways
Drugs
Diseases
GWAS		Periventricular white matter hyperintensities ( 32517579) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)	Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Monocyte percentage of white cells ( 32888494)
Interacting Genes		17 interacting genes: APP CSK DNAH1 DTX1 EPHA8 FBXO25 HAND1 HMGXB3 IL7R LCK LINC01554 OGT PIN1 PPIA RASA1 SYNPO USP10	8 interacting genes: ANXA7 CDK4 CDKN1A G3BP1 NDST1 PFDN1 SMN1 TK1
Entrez ID		10146	22993
HPRD ID		06569	19515
Ensembl ID		ENSG00000145907	ENSG00000113716
Uniprot IDs		Q13283 Q5U0Q1 Q6ZP53	Q12766 Q562E5
PDB IDs		3Q90 4FCJ 4FCM 4IIA 5FW5
Enriched GO Terms of Interacting Partners?
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