TRIM10 and ZNF148

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TRIM10	ZNF148
Description		tripartite motif containing 10	zinc finger protein 148
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Golgi Apparatus
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Biological_process Regulation Of Gene Expression Protein Ubiquitination Erythrocyte Differentiation Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Neuroticism ( 29255261) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Urate levels ( 31578528)
Interacting Genes		17 interacting genes: GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620	26 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 IFT122 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12
Entrez ID		10107	7707
HPRD ID		05752	03540
Ensembl ID		ENSG00000204613	ENSG00000163848
Uniprot IDs		A0A1U9X8M5 Q9UDY6	Q9UQR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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