STRIT1 and TSPAN15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STRIT1	TSPAN15
Description		small transmembrane regulator of ion transport 1	tetraspanin 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Sarcoplasmic Reticulum Membrane	Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Nuclear Body Cell Junction Late Endosome Membrane Intracellular Membrane-bounded Organelle Tetraspanin-enriched Microdomain
	Molecular Function	Protein Binding Enzyme Activator Activity	Protein Binding Enzyme Binding
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Regulation Of Catalytic Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Regulation Of Notch Signaling Pathway Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS			Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Response to taxane treatment (placlitaxel) ( 23006423) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombosis ( 26908601) Type 2 diabetes ( 32499647) Venous thromboembolism ( 25772935 28373160 31420334 31676865)
Interacting Genes		45 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R F11R FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35C2 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	14 interacting genes: ADAMDEC1 BTRC CHI3L1 GYPC KLRC3 RGS2 RUFY2 SERBP1 SETDB1 SLC25A16 STRIT1 SYNE4 TCHP TSPO
Entrez ID		100507537	23555
HPRD ID			15511
Ensembl ID		ENSG00000240045	ENSG00000099282
Uniprot IDs			O95858
PDB IDs
Enriched GO Terms of Interacting Partners?
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