RANBP9 and CACNA1G

Number of citations of the paper that reports this interaction (PubMedID 18801335)
7

Data Source:
BioGRID (two hybrid)

		RANBP9	CACNA1G
Description		RAN binding protein 9	calcium voltage-gated channel subunit alpha1 G
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Voltage-gated Sodium Channel Complex Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex Neuron Projection Synapse
	Molecular Function	Protein Binding Enzyme Binding Small GTPase Binding	Voltage-gated Sodium Channel Activity Low Voltage-gated Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Scaffold Protein Binding
	Biological Process	Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Sinoatrial Node Development Chemical Synaptic Transmission Response To Nickel Cation Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Action Potential SA Node Cell Action Potential AV Node Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Signaling AV Node Cell To Bundle Of His Cell Signaling Membrane Depolarization During AV Node Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	NCAM1 interactions
Drugs			Ergocalciferol Enflurane Trimethadione Spironolactone Cinnarizine Ethosuximide Verapamil Zonisamide Nifedipine Mibefradil Flunarizine Methsuximide Cannabidiol Trimebutine Benidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Breast cancer ( 29059683 23535729)	Adventurousness ( 30643258) Alzheimer's disease (cognitive decline) ( 23535033) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Total cholesterol levels ( 30498476)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 ZBED1	3 interacting genes: MKS1 RANBP9 UBQLN4
Entrez ID		10048	8913
HPRD ID		04835	04961
Ensembl ID		ENSG00000010017	ENSG00000006283
Uniprot IDs		A0A024QZW3 Q96S59	O43497
PDB IDs		5JI7 5JI9 5JIU	6KZO 6KZP
Enriched GO Terms of Interacting Partners?
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