FRAT1 and TDRD7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

		FRAT1	TDRD7
Description		FRAT regulator of WNT signaling pathway 1	tudor domain containing 7
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GO Annotations	Cellular Component	Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Mitochondrial Matrix Chromatoid Body Ribonucleoprotein Granule
	Molecular Function	Protein Binding	MRNA Binding Protein Binding Protein N-terminus Binding
	Biological Process	Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway	Lens Morphogenesis In Camera-type Eye Spermatogenesis Posttranscriptional Regulation Of Gene Expression Lens Fiber Cell Differentiation
Pathways		Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane
Drugs
Diseases
GWAS		Liver enzyme levels (alanine transaminase) ( 33972514) Lymphocyte counts ( 32888494) White blood cell count ( 32888494)	Bisphosphonate-associated atypical femoral fracture ( 31006051) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		13 interacting genes: DVL1 GPRASP2 GRN GSK3B KCNK5 KRT18 LAMC3 LMAN2 LTBP4 PLSCR1 PSMA3 RABEP2 TDRD7	23 interacting genes: ATXN2 BUB1 CABLES1 CCND1 CDK17 CDKN2A CTNNA1 DCC DLC1 FRAT1 FXR1 GABPB1 MAGEA8 MLH1 MLH3 MSH2 MUTYH NLGN3 NRAS ODC1 SHANK3 STK11 TACC1
Entrez ID		10023	23424
HPRD ID		03935	11626
Ensembl ID		ENSG00000165879	ENSG00000196116
Uniprot IDs		Q92837	Q8NHU6
PDB IDs		1GNG 3ZRK 3ZRL 3ZRM 4AFJ 5OY4	3RCO
Enriched GO Terms of Interacting Partners?
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