ZBTB33 and GSDMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZBTB33	GSDMD
Description		zinc finger and BTB domain containing 33	gasdermin D
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Extracellular Region Extracellular Space Nucleoplasm Cytosol Plasma Membrane Integral Component Of Membrane Specific Granule Lumen NLRP3 Inflammasome Complex Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Cardiolipin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated	Inflammatory Response Cellular Response To Extracellular Stimulus Positive Regulation Of Interleukin-1 Beta Production Pore Formation In Membrane Of Other Organism Defense Response To Bacterium Innate Immune Response Pore Complex Assembly Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Protein Homooligomerization Pyroptosis
Pathways			Release of apoptotic factors from the mitochondria Interleukin-1 processing Pyroptosis Regulation of TLR by endogenous ligand Neutrophil degranulation Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Monocyte count ( 32888494) Schizophrenia ( 31268507)
Interacting Genes		11 interacting genes: CBFA2T3 CTNND1 GSDMD GYS1 NCOR1 NUDT22 PLS3 SELENOS SUMO2 SUMO3 TRIML2	8 interacting genes: ASPG KCTD6 MEOX2 MFHAS1 PSMA1 ZBTB33 ZNF426 ZNF558
Entrez ID		10009	79792
HPRD ID		02269	11014
Ensembl ID		ENSG00000177485	ENSG00000104518
Uniprot IDs		Q86T24	P57764
PDB IDs		2LT7 3FKC 3M4T 3M8V 4F6M 4F6N 5VMU 5VMV 5VMW 5VMX 5VMY 5VMZ 6DF5 6DF8 6DF9 6DFA 6DFB 6DFC 6V8U	5NH1 5WQT 6AO4 6KN0 6N9O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?