MIS12

Description		MIS12 kinetochore complex component
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Kinetochore Nuclear MIS12/MIND Complex Nucleus Cytosol
	Molecular Function	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Chromosome Segregation Protein Localization To Kinetochore Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: AKT1 CBX3 CBX5 DSN1 HSP90AA1 KLHDC2 KNL1 NDC80 NSL1 PMF1 SUGT1 ZWINT
Entrez ID		79003
HPRD ID		12379
Ensembl ID		ENSG00000167842
Uniprot IDs		A8K1M4 Q9H081
PDB IDs		5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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