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TPI1

Description triosephosphate isomerase 1
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Nucleus
  • Cytosol
  • Extracellular Exosome
Molecular Function
  • Triose-phosphate Isomerase Activity
  • Protein Binding
  • Methylglyoxal Synthase Activity
  • Ubiquitin Protein Ligase Binding
  • Protein Homodimerization Activity
Biological Process
  • Gluconeogenesis
  • Glycolytic Process
  • Methylglyoxal Biosynthetic Process
  • Glycerol Catabolic Process
  • Glyceraldehyde-3-phosphate Biosynthetic Process
Pathways
  • Glycolysis
  • Gluconeogenesis
Drugs
  • Zinc
  • N-Hydroxy-4-Phosphono-Butanamide
  • 2-Phosphoglycolic Acid
  • Phosphoglycolohydroxamic Acid
  • 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
  • [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
  • 5-fluorotryptophan
  • 2-Carboxyethylphosphonic Acid
  • tert-butanol
  • Dihydroxyacetone phosphate
  • 1,4-Dithiothreitol
  • 3-phospho-D-glyceric acid
  • 3-(BUTYLSULPHONYL)-PROPANOIC ACID
  • Artenimol
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Refractive error ( 32231278)
Interacting Genes 17 interacting genes: APP BDKRB2 CCL11 CDKN2A CFL1 DDX24 EGFR HTR2C LIPT1 MAPK6 PCNA POT1 SETDB1 SP1 TERF1 UCHL5 YWHAQ
Entrez ID 7167
HPRD ID 01833
Ensembl ID ENSG00000111669
Uniprot IDs P60174 Q53HE2 V9HWK1
PDB IDs 1HTI 1KLG 1KLU 1WYI 2IAM 2IAN 2JK2 2VOM 4BR1 4E41 4POC 4POD 4UNK 4UNL 4ZVJ 6C2G 6D43 6NLH 6UP1 6UP5 6UP8 6UPF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025