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TESK1
Description
testis associated actin remodelling kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Lamellipodium
Cytoplasmic Vesicle
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Protein Kinase Binding
Metal Ion Binding
Protein Serine Kinase Activity
Biological Process
Positive Regulation Of Protein Phosphorylation
Spermatogenesis
Peptidyl-tyrosine Phosphorylation
Actin Cytoskeleton Organization
Negative Regulation Of Protein Autophosphorylation
Regulation Of Protein Localization
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Phosphorylation
Positive Regulation Of Stress Fiber Assembly
Establishment Of Vesicle Localization
Negative Regulation Of Protein Serine/threonine Kinase Activity
Glomerular Visceral Epithelial Cell Migration
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cilium Assembly
Pathways
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Fostamatinib
Diseases
GWAS
Interacting Genes
8 interacting genes:
ABCB4
ARAF
CFL1
IL17RA
PFKL
SPRY4
YWHAB
YY1
Entrez ID
7016
HPRD ID
03470
Ensembl ID
ENSG00000107140
Uniprot IDs
Q15569
Q8NFJ4
PDB IDs
Enriched GO Terms of Interacting Partners
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