SLC22A3

Description		solute carrier family 22 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuronal Cell Body Presynapse
	Molecular Function	Neurotransmitter Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Organic Anion Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity
	Biological Process	Histamine Metabolic Process Neurotransmitter Transport Organic Cation Transport Quaternary Ammonium Group Transport Organic Anion Transport Monocarboxylic Acid Transport Monoamine Transport Regulation Of Appetite Xenobiotic Transport Serotonin Uptake Histamine Uptake Norepinephrine Uptake Epinephrine Uptake Purine-containing Compound Transmembrane Transport Dopamine Uptake Transport Across Blood-brain Barrier Toxin Transport
Pathways		Abacavir transmembrane transport Organic cation transport
Drugs
Diseases
GWAS		Body fat percentage and LDL-C (pairwise) ( 33619380) Body fat percentage and triglycerides (pairwise) ( 33619380) Body mass index ( 26426971 28892062) Body mass index (age>50) ( 26426971) Body mass index and coronary artery disease (pairwise) ( 33619380) Body mass index and LDL-C (pairwise) ( 33619380) Body mass index and systole blood pressure (pairwise) ( 33619380) Body mass index and triglycerides (pairwise) ( 33619380) Body mass index x sex x age interaction (4df test) ( 26426971) Body shape index ( 34021172) Colorectal cancer ( 21242260) Coronary artery disease ( 24262325 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 19198611) Estimated glomerular filtration rate ( 31015462) Glycine levels ( 30837465) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Lipoprotein (a) levels ( 26377243) Lipoprotein (a) levels in response to niacin in statin-treated individuals ( 30371334) Lp (a) levels ( 21900290) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Plasma plasminogen levels ( 25208887) Prostate cancer ( 18264097 26034056 25939597 27262462) Pulse pressure ( 30224653) Response to hepatitis C treatment ( 22095909) Type 2 diabetes ( 30054458 30297969 28869590) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: PDZD3
Entrez ID		6581
HPRD ID		05328
Ensembl ID		ENSG00000146477
Uniprot IDs		O75751
PDB IDs
Enriched GO Terms of Interacting Partners?
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