KNL1

Description		kinetochore scaffold 1
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GO Annotations	Cellular Component	Kinetochore Acrosomal Vesicle Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding
	Biological Process	Acrosome Assembly Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Kinetochore Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		7 interacting genes: BUB1 BUB1B DSN1 MIS12 PAK6 PPP1CA TTK
Entrez ID		57082
HPRD ID		10634
Ensembl ID		ENSG00000137812
Uniprot IDs		Q8NG31
PDB IDs		3SI5 4A1G 4NF9 4NFA
Enriched GO Terms of Interacting Partners?
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