ACKR3

Description		atypical chemokine receptor 3
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GO Annotations	Cellular Component	Nucleus Endosome Early Endosome Plasma Membrane Clathrin-coated Pit External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Scavenger Receptor Activity Protein Binding Coreceptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding C-X-C Chemokine Binding
	Biological Process	Angiogenesis Vasculogenesis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Cell Population Proliferation Calcium-mediated Signaling Receptor Internalization Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Mesenchymal Stem Cell Migration
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Disease progression in age-related macular degeneration ( 29346644) Heel bone mineral density ( 30598549) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: ATP13A2 TP53
Entrez ID		57007
HPRD ID		09882
Ensembl ID		ENSG00000144476
Uniprot IDs		P25106
PDB IDs		6K3F
Enriched GO Terms of Interacting Partners?
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