PC

Description		pyruvate carboxylase
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Pyruvate Carboxylase Activity Protein Binding ATP Binding Biotin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Pyruvate Metabolic Process Gluconeogenesis Lipid Metabolic Process Negative Regulation Of Gene Expression Viral RNA Genome Packaging Positive Regulation By Host Of Viral Release From Host Cell Positive Regulation By Host Of Viral Process
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Gluconeogenesis
Drugs		Pyruvic acid Biotin 5-(hexahydro-2-oxo-1H-thieno[3,4-D]imidazol-6-yl)pentanal
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Body shape index ( 34021172) Familial squamous cell lung carcinoma ( 29924316) Hip circumference adjusted for BMI ( 34021172) HIV-1 susceptibility ( 22174851) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		6 interacting genes: GOT1 GOT2 MDH2 MYO7A PCBP2 SERPINH1
Entrez ID		5091
HPRD ID		02032
Ensembl ID		ENSG00000173599
Uniprot IDs		A0A024R5C5 P11498
PDB IDs		3BG3 3BG9
Enriched GO Terms of Interacting Partners?
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