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NSDHL

Description NAD(P) dependent steroid dehydrogenase-like
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Integral Component Of Membrane
Molecular Function
  • C-3 Sterol Dehydrogenase (C-4 Sterol Decarboxylase) Activity
  • 3-beta-hydroxy-delta5-steroid Dehydrogenase Activity
  • Protein Binding
  • Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
  • Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) Activity
  • 3-beta-hydroxysteroid Dehydrogenase/C4-decarboxylase Activity
  • 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) Activity
  • 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) Activity
Biological Process
  • Hair Follicle Development
  • Cholesterol Biosynthetic Process
  • Smoothened Signaling Pathway
  • Cholesterol Metabolic Process
  • Labyrinthine Layer Blood Vessel Development
Pathways
  • Cholesterol biosynthesis
Drugs
  • NADH
Diseases
GWAS
  • Glycated hemoglobin levels ( 34059833)
Interacting Genes 5 interacting genes: DCC GPR35 RHBDD1 TMEM31 TMX2
Entrez ID 50814
HPRD ID 02229
Ensembl ID ENSG00000147383
Uniprot IDs A0A384NPZ7 Q15738
PDB IDs 6JKG 6JKH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025