CNOT4

Description		CCR4-NOT transcription complex subunit 4
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GO Annotations	Cellular Component	Nucleus Cytosol CCR4-NOT Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Megakaryocyte Differentiation Protein Autoubiquitination
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
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Diseases
GWAS		Appendicular lean mass ( 33097823) Clostridioides difficle infection ( 33841421) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Meat-related diet ( 32066663) Numerical cognitive ability ( 31620175)
Interacting Genes		18 interacting genes: CNOT1 CNOT2 CNOT3 CNOT6 CNOT8 EP300 IL36RN KDM5C RBM15 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W
Entrez ID		4850
HPRD ID		05369
Ensembl ID		ENSG00000080802
Uniprot IDs		A0A024R776 A0A024R781 A0A024R785 O95628
PDB IDs		1E4U 1UR6
Enriched GO Terms of Interacting Partners?
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