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IFNAR2

Description interferon alpha and beta receptor subunit 2
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GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Cytokine Receptor Activity
  • Type I Interferon Receptor Activity
  • Protein Binding
  • Protein Kinase Binding
Biological Process
  • Cell Surface Receptor Signaling Pathway
  • Receptor Signaling Pathway Via JAK-STAT
  • Response To Virus
  • Cytokine-mediated Signaling Pathway
  • Response To Interferon-alpha
  • Response To Interferon-beta
  • Defense Response To Virus
  • Type I Interferon Signaling Pathway
Pathways
Drugs
  • Peginterferon alfa-2a
  • Interferon alfa-n1
  • Interferon alfa-n3
  • Peginterferon alfa-2b
  • Interferon alfa-2a, Recombinant
  • Interferon beta-1a
  • Interferon beta-1b
  • Interferon alfacon-1
  • Interferon alfa-2b
  • Human interferon omega-1
  • Nylidrin
Diseases
GWAS
  • Attention deficit hyperactivity disorder ( 30563984)
  • Cerebellum white matter volume ( 31530798)
  • Crohn's disease ( 23128233)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Type 2 diabetes ( 30130595)
Interacting Genes 15 interacting genes: HLCS IFNA2 IFNA5 IFNA8 IFNAR1 IFNB1 JAK1 PPP1R3B PRKCB RACK1 STAT1 STAT2 STAT3 TYK2 USP18
Entrez ID 3455
HPRD ID 03850
Ensembl ID ENSG00000159110
Uniprot IDs P48551 Q9BUA0
PDB IDs 1N6U 1N6V 2HYM 2KZ1 2LAG 3S8W 3S9D 3SE3 3SE4
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025