DKK3

Description		dickkopf WNT signaling pathway inhibitor 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space
	Molecular Function	Protein Binding Co-receptor Binding Receptor Antagonist Activity
	Biological Process	Anatomical Structure Morphogenesis Wnt Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Adrenal Gland Development Negative Regulation Of Aldosterone Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Anti-Mullerian Hormone Signaling Pathway Negative Regulation Of Cortisol Biosynthetic Process Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Cortical volume ( 32963231) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Response to perphenazine in schizophrenia ( 29503163) Response to taxane treatment (docetaxel) ( 23006423) Visceral fat ( 22589738) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: APC AURKA BCAR3 ESR2 FZR1 HOXA1 IDH1 NUFIP2 PPM1D SGTA SMAD4 UBQLN4
Entrez ID		27122
HPRD ID		05659
Ensembl ID		ENSG00000050165
Uniprot IDs		F6SYF8 Q9UBP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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