PADI4

Description		peptidyl arginine deiminase 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein-arginine Deiminase Activity Calcium Ion Binding Protein Binding Arginine Binding Identical Protein Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Chromatin Remodeling Cellular Protein Modification Process Protein Citrullination Stem Cell Population Maintenance Histone H3-R26 Citrullination Histone Citrullination Innate Immune Response
Pathways		Chromatin modifying enzymes
Drugs		Citrulline Azithromycin Tetracycline Streptomycin N-[(1S)-1-(aminocarbonyl)-4-(ethanimidoylamino)butyl]benzamide
Diseases
GWAS		Autoimmune traits (pleiotropy) ( 30572963) Basal cell carcinoma ( 18849993) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) IgA nephropathy ( 32912934 25305756) Rheumatoid arthritis ( 21452313 32723749 21505073 30423114 30572963 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		13 interacting genes: ANXA4 APP FBXO25 H3C15 HDAC2 LRRK2 NPM1 OTUD3 PADI2 POU6F2 SMURF1 SZRD1 TRIB3
Entrez ID		23569
HPRD ID		05635
Ensembl ID		ENSG00000159339
Uniprot IDs		Q9UM07
PDB IDs		1WD8 1WD9 1WDA 2DEW 2DEX 2DEY 2DW5 3APM 3APN 3B1T 3B1U 4DKT 4X8C 4X8G 5N0M 5N0Y 5N0Z 5N1B
Enriched GO Terms of Interacting Partners?
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