Respiratory - Wiki-CORONA

Symbols	Name 1	Name 2	Pathways 2 Hide	Drugs 2 Hide	Diseases 2 Hide
DACH1 and NCOR1	dachshund family transcription factor 1	nuclear receptor corepressor 1	Nuclear signaling by ERBB4 Nuclear signaling by ERBB4 NR1D1 (REV-ERBA) represses gene expression PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Transcriptional activation of mitochondrial biogenesis Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of SMAD2/3:SMAD4 transcriptional activity Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants HDACs deacetylate histones Notch-HLH transcription pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Nuclear Receptor transcription pathway Regulation of lipid metabolism by PPARalpha Circadian Clock Circadian Clock Activation of anterior HOX genes in hindbrain development during early embryogenesis Loss of MECP2 binding ability to the NCoR/SMRT complex Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux HCMV Early Events NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
DACH1 and JUN	dachshund family transcription factor 1	Jun proto-oncogene, AP-1 transcription factor subunit	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) FCERI mediated MAPK activation Activation of the AP-1 family of transcription factors Activation of anterior HOX genes in hindbrain development during early embryogenesis MAPK6/MAPK4 signaling TP53 Regulates Transcription of DNA Repair Genes Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Regulation of PTEN gene transcription Regulation of PTEN gene transcription Estrogen-dependent gene expression WNT5:FZD7-mediated leishmania damping	Vinblastine Pseudoephedrine Irbesartan Arsenic trioxide LGD-1550
DACH1 and TEAD2	dachshund family transcription factor 1	TEA domain transcription factor 2	YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
DACH1 and PPIG	dachshund family transcription factor 1	peptidylprolyl isomerase G		L-Proline
DACH1 and TCF3	dachshund family transcription factor 1	transcription factor 3	Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
DACH1 and NAGK	dachshund family transcription factor 1	N-acetylglucosamine kinase	Synthesis of UDP-N-acetyl-glucosamine	N-Acetylglucosamine
DACH1 and UBE2I	dachshund family transcription factor 1	ubiquitin conjugating enzyme E2 I	Meiotic synapsis Vitamin D (calciferol) metabolism SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMOylation of DNA damage response and repair proteins SUMO E3 ligases SUMOylate target proteins SUMOylation of transcription factors SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins SUMOylation of transcription cofactors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins SUMOylation of DNA methylation proteins SUMOylation of DNA methylation proteins SUMOylation of immune response proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Postmitotic nuclear pore complex (NPC) reformation
DACH1 and ZCCHC10	dachshund family transcription factor 1	zinc finger CCHC-type containing 10
DACH1 and MYCBP2	dachshund family transcription factor 1	MYC binding protein 2
DACH1 and EYA3	dachshund family transcription factor 1	EYA transcriptional coactivator and phosphatase 3	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
DACH1 and NFIC	dachshund family transcription factor 1	nuclear factor I C	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
DACH1 and C1orf35	dachshund family transcription factor 1	chromosome 1 open reading frame 35	Neutrophil degranulation
DACH1 and FOXO1	dachshund family transcription factor 1	forkhead box O1	AKT phosphorylates targets in the nucleus Regulation of gene expression in beta cells AKT-mediated inactivation of FOXO1A Constitutive Signaling by AKT1 E17K in Cancer MAPK6/MAPK4 signaling Interleukin-4 and Interleukin-13 signaling Regulation of localization of FOXO transcription factors FOXO-mediated transcription of cell death genes FOXO-mediated transcription of cell death genes FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Regulation of FOXO transcriptional activity by acetylation Regulation of FOXO transcriptional activity by acetylation FOXO-mediated transcription of cell cycle genes FOXO-mediated transcription of cell cycle genes		Alveolar rhabdomyosarcoma
DACH1 and U2AF2	dachshund family transcription factor 1	U2 small nuclear RNA auxiliary factor 2	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
DACH1 and FGF12	dachshund family transcription factor 1	fibroblast growth factor 12	Phase 0 - rapid depolarisation
DACH1 and NF2	dachshund family transcription factor 1	neurofibromin 2	Regulation of actin dynamics for phagocytic cup formation RHO GTPases activate PAKs		Malignant pleural mesothelioma Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
DACH1 and SIN3A	dachshund family transcription factor 1	SIN3 transcription regulator family member A	SUMOylation of transcription cofactors Regulation of lipid metabolism by PPARalpha NoRC negatively regulates rRNA expression RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Loss of MECP2 binding ability to 5mC-DNA Regulation of MECP2 expression and activity MECP2 regulates neuronal receptors and channels MECP2 regulates transcription of neuronal ligands FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Factors involved in megakaryocyte development and platelet production
DACH1 and EYA1	dachshund family transcription factor 1	EYA transcriptional coactivator and phosphatase 1	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks		Contiguous gene deletion syndrome involving EYA1, including: Oto-facio-cervical syndrome (OFC); Branchiootic syndrome 1 (BOS1); Branchio-oto-renal syndrome (BOR)
DACH1 and SIX1	dachshund family transcription factor 1	SIX homeobox 1
DACH1 and AHCYL1	dachshund family transcription factor 1	adenosylhomocysteinase like 1	PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

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