Wiki-CORONA

Search Results for: Respiratory

2697 interactions found:

Sort by: Relevance Number of Pathways Number of Drugs Number of Diseases
Symbols Name 1 Name 2
Pathways 1
Pathways 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
COL6A1 and MTDH collagen type VI alpha 1 chain metadherin
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A1 and MLLT3 collagen type VI alpha 1 chain MLLT3 super elongation complex subunit
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Formation of RNA Pol II elongation complex
  • RNA Polymerase II Pre-transcription Events
  • RNA Polymerase II Transcription Elongation
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A1 and PEX26 collagen type VI alpha 1 chain peroxisomal biogenesis factor 26
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Peroxisomal protein import
  • Peroxisomal protein import
  • Class I peroxisomal membrane protein import
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
COL6A1 and LGALS3BP collagen type VI alpha 1 chain galectin 3 binding protein
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Platelet degranulation
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A1 and PCNT collagen type VI alpha 1 chain pericentrin
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • Aggrephagy
  • Aggrephagy
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II)
  • Seckel syndrome
COL6A2 and FN1 collagen type VI alpha 2 chain fibronectin 1
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Platelet degranulation
  • Degradation of the extracellular matrix
  • Degradation of the extracellular matrix
  • Extracellular matrix organization
  • Fibronectin matrix formation
  • Cell surface interactions at the vascular wall
  • Molecules associated with elastic fibres
  • Integrin cell surface interactions
  • Syndecan interactions
  • Non-integrin membrane-ECM interactions
  • ECM proteoglycans
  • Integrin signaling
  • GRB2:SOS provides linkage to MAPK signaling for Integrins
  • p130Cas linkage to MAPK signaling for integrins
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • MAP2K and MAPK activation
  • Interleukin-4 and Interleukin-13 signaling
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by high-kinase activity BRAF mutants
  • Signaling by BRAF and RAF fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • MET activates PTK2 signaling
  • Post-translational protein phosphorylation
  • Signaling downstream of RAS mutants
  • Zinc
  • Ocriplasmin
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A2 and ABCD3 collagen type VI alpha 2 chain ATP binding cassette subfamily D member 3
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • ABC transporters in lipid homeostasis
  • Class I peroxisomal membrane protein import
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A2 and SIRPA collagen type VI alpha 2 chain signal regulatory protein alpha
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Cell surface interactions at the vascular wall
  • Signal regulatory protein family interactions
  • Signal regulatory protein family interactions
  • Neutrophil degranulation
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A2 and SLC38A3 collagen type VI alpha 2 chain solute carrier family 38 member 3
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Amino acid transport across the plasma membrane
  • Histidine
  • L-Asparagine
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
COL6A3 and MMP2 collagen type VI alpha 3 chain matrix metallopeptidase 2
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Collagen degradation
  • Collagen degradation
  • Degradation of the extracellular matrix
  • Degradation of the extracellular matrix
  • Activation of Matrix Metalloproteinases
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • EPH-ephrin mediated repulsion of cells
  • Interleukin-4 and Interleukin-13 signaling
  • Extra-nuclear estrogen signaling
  • Marimastat
  • Captopril
  • SC-74020
  • Halofuginone
  • AE-941
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Choriocarcinoma
  • Penile cancer
  • Torg-Winchester syndrome
COL6A3 and PPT1 collagen type VI alpha 3 chain palmitoyl-protein thioesterase 1
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Fatty acyl-CoA biosynthesis
  • 1-Hexadecylsulfonyl Fluoride
  • Palmitic Acid
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
  • Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
COL8A2 and LMNA collagen type VIII alpha 2 chain lamin A/C
  • Collagen degradation
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • Collagen chain trimerization
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Posterior polymorphous corneal dystrophy (PPCD)
  • Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
COL17A1 and PLEC collagen type XVII alpha 1 chain plectin
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Assembly of collagen fibrils and other multimeric structures
  • Type I hemidesmosome assembly
  • Collagen chain trimerization
  • Assembly of collagen fibrils and other multimeric structures
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Type I hemidesmosome assembly
  • Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Epidermolysis bullosa, hemidesmosomal, including: Epidermolysis bullosa, generalized atrophic benign (GABEB); Epidermolysis bullosa simplex with pyloric atresia (EBS-PA); Epidermolysis bullosa simplex with muscular dystrophy (EBS-MD); Epidermolysis bullosa simplex, Ogna type (EBS-Ogna)
COMT and HCK catechol-O-methyltransferase HCK proto-oncogene, Src family tyrosine kinase
  • Methylation
  • Enzymatic degradation of dopamine by COMT
  • Enzymatic degradation of Dopamine by monoamine oxidase
  • Nef and signal transduction
  • FCGR activation
  • Regulation of signaling by CBL
  • Regulation of signaling by CBL
  • FLT3 Signaling
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated phagocytosis
  • Ademetionine
  • Tolcapone
  • Entacapone
  • 3,5-Dinitrocatechol
  • 2-Methoxyestradiol
  • BIA
  • N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide
  • Nialamide
  • (3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE
  • 7,8-dihydroxy-4-phenyl-2H-chromen-2-one
  • 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
  • Phosphonotyrosine
  • Quercetin
  • Bosutinib
COPB1 and HLA-DPB1 COPI coat complex subunit beta 1 major histocompatibility complex, class II, DP beta 1
  • Neutrophil degranulation
  • COPI-mediated anterograde transport
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Downstream TCR signaling
  • Phosphorylation of CD3 and TCR zeta chains
  • Translocation of ZAP-70 to Immunological synapse
  • Generation of second messenger molecules
  • MHC class II antigen presentation
  • PD-1 signaling
  • Interferon gamma signaling
  • Dilated cardiomyopathy (DCM)
COX6A2 and POT1 cytochrome c oxidase subunit 6A2 protection of telomeres 1
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Telomere Extension By Telomerase
  • DNA Damage/Telomere Stress Induced Senescence
  • Cholic Acid
  • N-Formylmethionine
COX6A2 and SNX21 cytochrome c oxidase subunit 6A2 sorting nexin family member 21
  • Cholic Acid
  • N-Formylmethionine
COX6A2 and MRPL12 cytochrome c oxidase subunit 6A2 mitochondrial ribosomal protein L12
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
  • Cholic Acid
  • N-Formylmethionine
COX6C and PTN cytochrome c oxidase subunit 6C pleiotrophin
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Cholic Acid
  • N-Formylmethionine
COX6C and RCHY1 cytochrome c oxidase subunit 6C ring finger and CHY zinc finger domain containing 1
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
  • Translesion Synthesis by POLH
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Cholic Acid
  • N-Formylmethionine

Page 39 out of 135 pages