Pulmonary - Wiki-CORONA

Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide	Drugs 2 Hide	Diseases 1 Hide	Diseases 2 Hide
ALDOA and PCNA	aldolase, fructose-bisphosphate A	proliferating cell nuclear antigen	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Transcription of E2F targets under negative control by DREAM complex Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Removal of the Flap Intermediate from the C-strand SUMOylation of DNA replication proteins Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand G1/S-Specific Transcription E3 ubiquitin ligases ubiquitinate target proteins	Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE	Liothyronine
ALOX5 and MAD1L1	arachidonate 5-lipoxygenase	mitotic arrest deficient 1 like 1	Synthesis of 5-eicosatetraenoic acids Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of Lipoxins (LX) Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation Interleukin-18 signaling Biosynthesis of D-series resolvins Biosynthesis of maresins Biosynthesis of E-series 18(S)-resolvins Biosynthesis of aspirin-triggered D-series resolvins Biosynthesis of E-series 18(R)-resolvins Biosynthesis of DPAn-3-derived protectins and resolvins Biosynthesis of DPAn-3-derived maresins Biosynthesis of DPAn-3-derived 13-series resolvins Biosynthesis of electrophilic Ï‰-3 PUFA oxo-derivatives	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Vitamin E Masoprocol Aminosalicylic Acid Mesalazine Montelukast Diclofenac Diethylcarbamazine Zileuton Sulfasalazine Meclofenamic acid Balsalazide Minocycline Hyperforin Resveratrol Licofelone MLN-977 Diacerein Rhein
AMPH and MAPT	amphiphysin	microtubule associated protein tau	Clathrin-mediated endocytosis	Caspase-mediated cleavage of cytoskeletal proteins		Lansoprazole Astemizole Paclitaxel Docetaxel		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3) Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
BIN1 and ASAP2	bridging integrator 1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	Clathrin-mediated endocytosis				Centronuclear myopathy
BIN1 and ITGA1	bridging integrator 1	integrin subunit alpha 1	Clathrin-mediated endocytosis	Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Other semaphorin interactions Smooth Muscle Contraction CHL1 interactions Platelet Adhesion to exposed collagen			Centronuclear myopathy
BIN1 and RIN3	bridging integrator 1	Ras and Rab interactor 3	Clathrin-mediated endocytosis	RAB GEFs exchange GTP for GDP on RABs			Centronuclear myopathy
ANK1 and KCTD6	ankyrin 1	potassium channel tetramerization domain containing 6	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation			Hereditary spherocytosis (SPH)
ANK1 and BLOC1S6	ankyrin 1	biogenesis of lysosomal organelles complex 1 subunit 6	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Golgi Associated Vesicle Biogenesis			Hereditary spherocytosis (SPH)
ANK1 and TIAM1	ankyrin 1	TIAM Rac1 associated GEF 1	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	NRAGE signals death through JNK Rho GTPase cycle EPHB-mediated forward signaling EPH-ephrin mediated repulsion of cells G alpha (12/13) signalling events Activated NTRK2 signals through CDK5			Hereditary spherocytosis (SPH)
ANK1 and SPTA1	ankyrin 1	spectrin alpha, erythrocytic 1	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport			Hereditary spherocytosis (SPH)	Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)
ANK1 and SPTAN1	ankyrin 1	spectrin alpha, non-erythrocytic 1	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport			Hereditary spherocytosis (SPH)	Early infantile epileptic encephalopathy; Ohtahara syndrome
ANK1 and SPTB	ankyrin 1	spectrin beta, erythrocytic	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport			Hereditary spherocytosis (SPH)	Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)
ANK1 and L1CAM	ankyrin 1	L1 cell adhesion molecule	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Basigin interactions L1CAM interactions L1CAM interactions Recycling pathway of L1 Recycling pathway of L1 Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins Signal transduction by L1		Ethanol	Hereditary spherocytosis (SPH)	Hereditary spastic paraplegia (SPG) Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) L1 syndrome, including: ; X-linked hydrocephalus; MASA syndrome; X-linked complicated spastic paraplegia type I ; X-linked partial agenesis of corpus callosum
ANK1 and RYR1	ankyrin 1	ryanodine receptor 1	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Stimuli-sensing channels Ion homeostasis		Caffeine Dantrolene Suramin Tetracaine	Hereditary spherocytosis (SPH)	Central core disease
ANK1 and CD44	ankyrin 1	CD44 molecule (Indian blood group)	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Degradation of the extracellular matrix Cell surface interactions at the vascular wall Integrin cell surface interactions Hyaluronan uptake and degradation Neutrophil degranulation Interferon gamma signaling		Hyaluronic acid	Hereditary spherocytosis (SPH)	Gastric cancer
ANK1 and OBSCN	ankyrin 1	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events			Hereditary spherocytosis (SPH)
ANK1 and NFASC	ankyrin 1	neurofascin	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation			Hereditary spherocytosis (SPH)
ANK1 and NBPF3	ankyrin 1	NBPF member 3	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport				Hereditary spherocytosis (SPH)
ANK1 and TTN	ankyrin 1	titin	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Platelet degranulation Striated Muscle Contraction			Hereditary spherocytosis (SPH)	Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Hypertrophic cardiomyopathy (HCM) Dilated cardiomyopathy (DCM)
ANK1 and SLC4A3	ankyrin 1	solute carrier family 4 member 3	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins NrCAM interactions CHL1 interactions Neurofascin interactions Neurofascin interactions COPI-mediated anterograde transport	Bicarbonate transporters			Hereditary spherocytosis (SPH)

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