NUP153 and IPO5

Number of citations of the paper that reports this interaction (PubMedID 9114010)
43

Data Source:
HPRD (in vivo, in vitro)

		NUP153	IPO5
Description		nucleoporin 153	importin 5
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Nucleolus Cytosol Membrane Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Host Cell Nuclear Pore Central Transport Channel Nuclear Pore Nuclear Basket	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane
	Molecular Function	DNA Binding Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein Membrane Anchor Metal Ion Binding	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Viral Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Viral Penetration Into Host Nucleus Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events	vRNP Assembly
Drugs
Diseases
GWAS		Height ( 18391951) Obesity-related traits ( 23251661)	Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		26 interacting genes: APC BRCA1 CLK1 DYNLT1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 MRPS5 NUP62 NUTF2 NXF1 NXF2 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-7 XPO1 XPO5 XPO7 XPOT	23 interacting genes: ACD BHLHB9 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL
Entrez ID		9972	3843
HPRD ID		04899	03597
Ensembl ID		ENSG00000124789	ENSG00000065150
Uniprot IDs		P49790	B3KWG6 O00410 Q9BVS9
PDB IDs		2EBQ 2EBR 2EBV 2GQE 4U0C 4U0D 5TSV 5TSX 6AYA
Enriched GO Terms of Interacting Partners?
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