CDC34 and MARCHF2

Number of citations of the paper that reports this interaction (PubMedID 14722266)
108

Data Source:
BioGRID (pull down)

		CDC34	MARCHF2
Description		cell division cycle 34, ubiqiutin conjugating enzyme	membrane associated ring-CH-type finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Speck	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Protein Ubiquitination Cellular Response To Interferon-beta Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly	Endocytosis Protein Ubiquitination
Pathways		Downstream TCR signaling FCERI mediated NF-kB activation CLEC7A (Dectin-1) signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		53 interacting genes: ATF5 BTRC CCNB1 CDK9 CDKN1B CREM CSNK2B CTNNB1 CUL1 CUL2 CUL3 FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCHF1 MARCHF2 MDM2 MUL1 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARA PPARG PRKN PTTG1 RBX1 RELA RNF31 RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TRIM21 TRIM28 TRIM29 UBA1 UBB UBC VHL WWP2 ZFAND6 ZNRF1	11 interacting genes: CDC34 CFTR ECSIT FATE1 FBXL12 KASH5 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H
Entrez ID		997	51257
HPRD ID		00306	14361
Ensembl ID		ENSG00000099804	ENSG00000099785
Uniprot IDs		A0A024R1Z1 P49427	Q9P0N8
PDB IDs		2OB4 3RZ3 4MDK
Enriched GO Terms of Interacting Partners?
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