CDC25A and NAA10

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (enzymatic study)
HPRD (two hybrid)

		CDC25A	NAA10
Description		cell division cycle 25A	N-alpha-acetyltransferase 10, NatA catalytic subunit
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Intracellular Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding Chaperone Binding	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Proliferation Response To Radiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Cellular Response To UV Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Cell Cycle Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle	DNA Packaging Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
Pathways		Transcription of E2F targets under negative control by DREAM complex Polo-like kinase mediated events Activation of ATR in response to replication stress Ub-specific processing proteases Cyclin E associated events during G1/S transition Cyclin A/B1/B2 associated events during G2/M transition Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Cyclin A:Cdk2-associated events at S phase entry Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878) Household income (MTAG) ( 31844048) Loneliness (multivariate analysis) ( 27629369) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 27618447)	Systemic lupus erythematosus ( 26502338)
Interacting Genes		55 interacting genes: APP AR BTRC CAMK1D CCNA1 CCNB1 CCNE1 CCNI CDK1 CDK2 CDK5 CDKN3 CHEK1 CHEK2 CSNK1A1 CUL3 CUX1 DMD DUSP8 EEF1A1 EGFR FAM193B FBXW11 FGF21 FTH1 FZR1 HDAC11 HLA-C HRAS IL3RA LMO2 MAP3K5 MAPK14 MCM3AP MTAP NAA10 NFKBIB NFYA PEX19 PIM1 PKM POLR1D RAF1 ROCK1 SCYL1 SMAD3 SOX5 SRC UBB VAMP8 XPO1 YWHAB YWHAE YWHAQ YWHAZ	29 interacting genes: BCOR CALCOCO2 CDC25A CEP44 CREB3 EHMT2 FIP1L1 HIF1A HIF1AN HSPA4 KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-7 MEOX2 NAA15 NAA16 NAA50 NAT1 NAT2 PDE4DIP PGK1 PSME2 RAB3IP RBCK1 RPL26 SSX2IP UBC ZBTB14
Entrez ID		993	8260
HPRD ID		00305	02056
Ensembl ID		ENSG00000164045	ENSG00000102030
Uniprot IDs		A0A024R2R6 D8KXX0 K7N7S0 P30304	B7Z9N2 P41227
PDB IDs		1C25	6C95 6C9M
Enriched GO Terms of Interacting Partners?
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