CDC5L and MYT1L

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		CDC5L	MYT1L
Description		cell division cycle 5 like	myelin transcription factor 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Cytoplasm Membrane Nuclear Speck Perinuclear Region Of Cytoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Protein Phosphatase 1 Binding Protein Kinase Binding Leucine Zipper Domain Binding WD40-repeat Domain Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Zinc Ion Binding
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome DNA Repair Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Interleukin-2 Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Wortmannin Cellular Response To Nerve Growth Factor Stimulus Cellular Response To Prolactin	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Nervous System Development Neuron Differentiation Neuron Fate Commitment Neuron Fate Specification Neuron Development
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Chin dimples ( 27182965) FEV1 ( 30804560) Height ( 28552196) Ischemic stroke ( 26089329) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Stroke (ischemic) ( 22941190)	Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Caudate nucleus volume ( 31530798) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diabetic retinopathy ( 21441570) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Glucose homeostasis traits ( 25524916) Gut microbiota (functional units) ( 27694959) Impulsivity ( 30718321) Impulsivity (motor) ( 30718321) Impulsivity (non-planning) ( 30718321) Inflammatory skin disease ( 25574825) Mitochondrial DNA copy number (white blood cells) ( 30704525) Moderate-to-late spontaneous preterm birth ( 31194736) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Systemic sclerosis ( 30247649) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Type 2 diabetes (age of onset) ( 28060188) Vitamin B levels in ischemic stroke ( 25147783)
Interacting Genes		69 interacting genes: AKAP6 AKAP9 BCAS2 BICRAL CALM1 CCDC136 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANSL1 KDM1A KIF3C KIF5B KRT18 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 TRAF3IP1 TRAK1 TRIO TTF2 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZSCAN1	3 interacting genes: AURKA CDC5L DISC1
Entrez ID		988	23040
HPRD ID		04184	14797
Ensembl ID		ENSG00000096401	ENSG00000186487
Uniprot IDs		Q99459	A0A2R8YF72 A0A3B3IRM3 A0A3B3IRX5 A0A3B3IS14 A0A3B3IS61 A0A3B3ISW5 Q9UL68
PDB IDs		2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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