CDK11B and TPPP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CDK11B	TPPP
Description		cyclin dependent kinase 11B	tubulin polymerization promoting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Mitochondrion Cytosol Microtubule Cell Junction Perinuclear Region Of Cytoplasm Mitotic Spindle Microtubule Bundle Postsynaptic Golgi Apparatus
	Molecular Function	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Magnesium Ion Binding GTPase Activity Protein Binding Microtubule Binding Tubulin Binding Protein Homodimerization Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of MRNA Processing	Microtubule Bundle Formation Oligodendrocyte Development Astral Microtubule Organization Positive Regulation Of Protein Complex Assembly Positive Regulation Of Myelination Positive Regulation Of Protein Polymerization Myelin Assembly Microtubule Polymerization Oligodendrocyte Differentiation Cell Division Microtubule Nucleation By Microtubule Organizing Center Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Tubulin Deacetylation
Pathways		Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Esophageal adenocarcinoma ( 27527254) Estimated glomerular filtration rate ( 31152163) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Ulcerative colitis ( 28067908 20228799)
Interacting Genes		24 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F KAT7 MSN PAK1 PIN1 PPIL3 RANBP9 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ	7 interacting genes: APP CDK11B GAPDH GSK3B HDAC6 SNCA TUBB
Entrez ID		984	11076
HPRD ID		08909	18522
Ensembl ID		ENSG00000248333	ENSG00000171368
Uniprot IDs		B4DII1 P21127	O94811 Q4L233
PDB IDs
Enriched GO Terms of Interacting Partners?
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