DNAJC6 and BAG2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		DNAJC6	BAG2
Description		DnaJ heat shock protein family (Hsp40) member C6	BAG cochaperone 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Postsynaptic Density Vesicle Intracellular Membrane-bounded Organelle Presynapse	Cytosol Microtubule Axon Dendrite Chaperone Complex Dendritic Microtubule
	Molecular Function	Protein Tyrosine Phosphatase Activity SH3 Domain Binding Clathrin Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ion Channel Binding Tau Protein Binding Chaperone Binding
	Biological Process	Receptor-mediated Endocytosis Synaptic Vesicle Uncoating Peptidyl-tyrosine Dephosphorylation Membrane Organization Clathrin Coat Disassembly Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Cellular Response To Heat Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Idiopathic osteonecrosis of the femoral head ( 28000841)
Interacting Genes		3 interacting genes: AP2A2 BAG2 CLTC	16 interacting genes: CCAR2 DAPK1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83
Entrez ID		9829	9532
HPRD ID		16326	04859
Ensembl ID		ENSG00000116675	ENSG00000112208
Uniprot IDs		O75061	O95816
PDB IDs
Enriched GO Terms of Interacting Partners?
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