RAPGEF5 and PLAC9

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		RAPGEF5	PLAC9
Description		Rap guanine nucleotide exchange factor 5	placenta associated 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Extracellular Region
	Molecular Function	Ras Guanyl-nucleotide Exchange Factor Activity Rap Guanyl-nucleotide Exchange Factor Activity GTP-dependent Protein Binding	Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Nervous System Development
Pathways
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Diastolic blood pressure ( 30224653) Glaucoma ( 30104761) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Night sleep phenotypes ( 27126917) Spatial processing ( 31596458) Squamous cell lung carcinoma ( 28604730) Thyroid stimulating hormone levels ( 17903292)	Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
Interacting Genes		7 interacting genes: MRAS PLAC9 RAP1A RAP2A RAP2B TMEM253 VANGL1	4 interacting genes: CCDC14 EMILIN1 RAPGEF5 RNF213
Entrez ID		9771	219348
HPRD ID		15208	18491
Ensembl ID		ENSG00000136237	ENSG00000189129
Uniprot IDs		A8MQ07 Q5JPD2 Q92565	Q5JTB5 Q5JTB6
PDB IDs		1WGY
Enriched GO Terms of Interacting Partners?
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