IFT140 and RANBP2

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		IFT140	RANBP2
Description		intraflagellar transport 140	RAN binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip	Nucleus Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Mitochondrion Cytosol Membrane Nuclear Membrane Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Cytoplasmic Periphery Of The Nuclear Pore Complex
	Molecular Function	Molecular_function Protein Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity GTPase Activator Activity Protein Binding Ran GTPase Binding Cyclosporin A Binding SUMO Transferase Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development	Protein Peptidyl-prolyl Isomerization Response To Amphetamine Regulation Of Glycolytic Process Regulation Of Gluconeogenesis MRNA Export From Nucleus TRNA Export From Nucleus Protein Folding NLS-bearing Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Positive Regulation Of Glucokinase Activity Positive Regulation Of GTPase Activity Centrosome Localization Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		Hedgehog 'off' state Intraflagellar transport	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)	Attention deficit hyperactivity disorder ( 29325848) Beard thickness ( 26926045) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2	35 interacting genes: AKAP13 ARID4B CALM1 CDCA8 CUL1 FHOD1 GCC2 HDAC4 IFT140 IPO5 KPNA1 KPNA2 KPNB1 LRPAP1 MAP2K7 MDM2 NUP62 NXF1 OPN1LW OPN1MW PRKN RAN RANGAP1 SENP1 SP100 SUMO1 SUMO2 TAF1 TNPO1 TOP2B UBE2I UBTD1 WAS XPO1 XPOT
Entrez ID		9742	5903
HPRD ID		11093	03111
Ensembl ID		ENSG00000187535	ENSG00000153201
Uniprot IDs		Q96RY7	P49792
PDB IDs			1RRP 1XKE 1Z5S 2LAS 3UIN 3UIO 3UIP 4GA0 4I9Y 4L6E 4LQW 5CLL 5CLQ
Enriched GO Terms of Interacting Partners?
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