RNF14 and NCOA4

Number of citations of the paper that reports this interaction (PubMedID 10085091)
46

Data Source:
HPRD (in vivo, in vitro)

		RNF14	NCOA4
Description		ring finger protein 14	nuclear receptor coactivator 4
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol	Cell Nucleus Autolysosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Androgen Receptor Binding
	Biological Process	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway	Protein Targeting To Lysosome Cellular Iron Ion Homeostasis Male Gonad Development Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Thyroid cancer
GWAS		Superior temporal gyrus volume ( 31530798)	Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mean corpuscular hemoglobin ( 29403010 20139978) Mean corpuscular volume ( 29403010 20139978) Red blood cell count ( 29403010)
Interacting Genes		24 interacting genes: AR DACH1 ESR1 FBN2 HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TENT5A TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2U UBE2V1 UBE2W VDR	11 interacting genes: AKT1 AR ATXN2 ESR1 GTF2B KAT2B NR3C1 PPARG RNF14 RXRA VDR
Entrez ID		9604	8031
HPRD ID		05745	03584
Ensembl ID		ENSG00000013561	ENSG00000266412
Uniprot IDs		B7Z229 Q9UBS8	A0A024QZI5 B2R5V0 Q13772 Q96E88
PDB IDs			1T5Z
Enriched GO Terms of Interacting Partners?
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