PTGES and PTGER1

Number of citations of the paper that reports this interaction (PubMedID 8253813)
48

Data Source:
HPRD (in vivo)

		PTGES	PTGER1
Description		prostaglandin E synthase	prostaglandin E receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Lumen Mitochondrion Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Cell Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Binding Prostaglandin-E Synthase Activity	Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Prostaglandin Biosynthetic Process Acute Inflammatory Response Chronic Inflammatory Response Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Negative Regulation Of Cell Proliferation Response To Organic Cyclic Compound Cyclooxygenase Pathway Response To Lipopolysaccharide Response To Retinoic Acid Response To Cytokine Response To Calcium Ion Oxidation-reduction Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipopolysaccharide Negative Regulation Of Gastric Emptying
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Bupivacaine Carboprost Tromethamine Alprostadil Bimatoprost Dinoprostone Iloprost Limaprost
Diseases
GWAS		Asthma ( 27611488) Pars orbitalis volume ( 31530798)
Interacting Genes		2 interacting genes: PTGER1 PTGER2	5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		9536	5731
HPRD ID		05528	08903
Ensembl ID		ENSG00000148344	ENSG00000160951
Uniprot IDs		O14684	P34995
PDB IDs		3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9
Enriched GO Terms of Interacting Partners?
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