POLR1C and TASOR2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		POLR1C	TASOR2
Description		RNA polymerase I and III subunit C	transcription activation suppressor family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex RNA Polymerase I Complex Cytosol	Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Gene Expression, Epigenetic
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases		Treacher Collins syndrome
GWAS		GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		35 interacting genes: ATRIP BIRC7 CBY2 CCDC33 CD3EAP CLU CORO1A CORO1B IHO1 IKZF3 KCTD1 KRT19 LNX2 LZTS2 MBIP MKRN3 MYD88 MYO5B NFKBIB NME1 POLR1D POLR1E PPP2R3C RIMBP3 SAXO1 SMN2 TASOR2 TCF4 TFIP11 TNFAIP1 TRIM27 TRIOBP TSC22D4 VIM WRN	23 interacting genes: ATRIP CARD9 CCDC85B CCNG2 COX5B ERH FBF1 HGS KCTD9 KLHL40 LDOC1 LMO1 MLH1 MORN3 NEK6 POLR1C PPP1R16B PRKAB2 SCAMP1 SMARCB1 STAT3 TRIM23 TRIM42
Entrez ID		9533	54906
HPRD ID		09661	10695
Ensembl ID		ENSG00000171453	ENSG00000108021
Uniprot IDs		O15160	Q5VWN6
PDB IDs
Enriched GO Terms of Interacting Partners?
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