TBPL1 and GTF2A2

Number of citations of the paper that reports this interaction (PubMedID 10570139)
39

Data Source:
HPRD (in vivo)

		TBPL1	GTF2A2
Description		TATA-box binding protein like 1	general transcription factor IIA subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor Complex Transcription Factor TFIIA Complex Cytoplasm	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cell Junction
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding	RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Acrosome Assembly DTTP Biosynthetic Process DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Spermatid Nucleus Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Height ( 28552196) Night sleep phenotypes ( 27126917)	Macular thickness ( 30535121)
Interacting Genes		16 interacting genes: ABCF3 APP FBXO7 GTF2A1 GTF2A2 GTF2B IRAK4 NDUFA6 NF1 PLIN3 PRNP PTCD3 RAB35 RPL10 SLC35F6 TNNT1	8 interacting genes: GTF2A1 GTF2A1L GTF2E1 HSF1 PTPN11 TAF4 TBP TBPL1
Entrez ID		9519	2958
HPRD ID		09272	02747
Ensembl ID		ENSG00000028839	ENSG00000140307
Uniprot IDs		P62380	A0A024R5Z5 B2R506 P52657
PDB IDs			1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L
Enriched GO Terms of Interacting Partners?
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