NMT2 and TMED9

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NMT2	TMED9
Description		N-myristoyltransferase 2	transmembrane p24 trafficking protein 9
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extrinsic Component Of Membrane Host Cell	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding	Protein Binding Syntaxin Binding
	Biological Process	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Transport Of Virus	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle
Pathways		Membrane binding and targetting of GAG proteins Inactivation, recovery and regulation of the phototransduction cascade	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Myristoyl-Coa S-(2-Oxo)Pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: ANXA4 ANXA7 APP BCL2 CASP3 CSNK2B PPP1CC PRKCZ SMN1 TK1 TMED9 TP53	8 interacting genes: CKMT2 COPZ1 DDX54 MAT2B MTF2 NMT2 SEC23B THAP8
Entrez ID		9397	54732
HPRD ID		11948	09975
Ensembl ID		ENSG00000152465	ENSG00000184840
Uniprot IDs		B3KT39 O60551 Q5VUC6	A0A024R7M0 Q9BVK6
PDB IDs		4C2X
Enriched GO Terms of Interacting Partners?
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