LONP1 and MAST1

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		LONP1	MAST1
Description		lon peptidase 1, mitochondrial	microtubule associated serine/threonine kinase 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Mitochondrial Nucleoid	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Mitochondrial Promoter Sequence-specific DNA Binding Single-stranded DNA Binding Single-stranded RNA Binding ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding ADP Binding Sequence-specific DNA Binding G-quadruplex DNA Binding DNA Polymerase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding
	Biological Process	Mitochondrial Genome Maintenance Response To Hypoxia Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Mitochondrion Organization Aging Response To Hormone Response To Aluminum Ion Mitochondrial DNA Metabolic Process Cellular Response To Oxidative Stress Chaperone-mediated Protein Complex Assembly Proteolysis Involved In Cellular Protein Catabolic Process Oxidation-dependent Protein Catabolic Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS			High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010) Monocyte count ( 27863252) Red blood cell count ( 29403010)
Interacting Genes		10 interacting genes: A2M APOE CDC37 CYP2C8 ECSIT IFIT3 IFIT5 LOXL4 MAST1 RNF32	38 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1
Entrez ID		9361	22983
HPRD ID		05689	17469
Ensembl ID		ENSG00000196365	ENSG00000105613
Uniprot IDs		P36776	Q9Y2H9
PDB IDs		2X36	2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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